At the outset of the U.S. Bone and Joint Decade in 2002, professional societies and patient advocacy organizations estimated that musculoskeletal research represented a significantly small proportion of all health research despite the prevalence of bone and joint disorders in America. As one key reason, they cited too few clinicians treating patients with these disorders willing to pursue a career in research. The solution: Experienced researchers involved in the U.S. Bone and Joint Decade (USBJD) developed the Young Investigators Initiative. Today that program has led to 1,066 new musculoskeletal research studies by 202 newly-funded investigators. Funding for these studies totals almost $270 million.